The Mississippi River has the fourth largest drainage basin or "catchment" in the world. The basin covers more than 1,245,000 sq mi (3,220,000 km2), including all or parts of 31 states and two Canadian provinces. The drainage basin empties into the Gulf of Mexico.
Major tributaries of the Mississippi:
* Big Black River in Mississippi
* Yazoo River in Mississippi
* Red River in Louisiana
* White River in Arkansas
* Arkansas River in Arkansas
* Ohio River in Kentucky
* Big Muddy River in Illinois
* Kaskaskia River in Illinois
* Missouri River in Missouri
* Illinois River in Illinois
* Des Moines River in Iowa
* Skunk River in Iowa
* Iowa River in Iowa
* Rock River in Illinois
* Maquoketa River in Iowa
* Wapsipinicon River in Iowa
* Wisconsin River in Wisconsin
* Chippewa River in Wisconsin
* St. Croix River in Minnesota and Wisconsin
* Minnesota River in Minnesota
* Crow River in Minnesota